Bilateral coordination of walking and freezing of gait in Parkinson’s disease
Identifieur interne : 000E58 ( Main/Exploration ); précédent : 000E57; suivant : 000E59Bilateral coordination of walking and freezing of gait in Parkinson’s disease
Auteurs : Meir Plotnik [Israël] ; Nir Giladi [Israël] ; Jeffrey M. Hausdorff [Israël, États-Unis]Source :
- European Journal of Neuroscience [ 0953-816X ] ; 2008-04.
English descriptors
Abstract
Freezing of gait (FOG) in Parkinson's disease (PD) occurs most frequently during turns or step initiation, two tasks that likely demand a high degree of bilateral coordination between the legs. Our objective was to test the hypothesis that impairments in bilateral coordination of stepping are associated with FOG in PD. We compared locomotion features while walking on level ground between patients with PD that experience FOG (PD + FOG; n = 21) and patients with PD that do not (PD − FOG; n = 13). To study bilateral stepping coordination, we defined the stride duration of one foot as a gait cycle or 360°, determined the relative timing of contralateral heel‐strikes and defined this as the phase, ϕ (ideally, ϕ = 180°). The sum of the coefficient of variation of ϕ and the mean absolute difference between ϕ and 180° was defined as the phase coordination index (PCI), representing variability and inaccuracy, respectively, in phase generation. During the ‘Off’ state (= 12 h off anti‐parkinsonian medication), PCI values were higher (poorer coordination) in PD + FOG compared with PD − FOG (P < 0.024). Stride‐to‐stride phase adjustments, Δϕ, were also studied. Both groups scaled their ‘converging’ adjustments (towards 180°) to the same extent, but when generating diverging Δϕ (away from 180°), PD + FOG patients exhibited larger errors compared with PD − FOG patients (P < 0.006). This study demonstrates that patients with PD who experience FOG have distinctive impairments in the bilateral coordination of locomotion. Poor bilateral coordination of walking may predispose to FOG, especially during challenging tasks that demand a high degree of left–right coordination.
Url:
DOI: 10.1111/j.1460-9568.2008.06167.x
Affiliations:
Links toward previous steps (curation, corpus...)
Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Bilateral coordination of walking and freezing of gait in Parkinson’s disease</title><author><name sortKey="Plotnik, Meir" sort="Plotnik, Meir" uniqKey="Plotnik M" first="Meir" last="Plotnik">Meir Plotnik</name></author><author><name sortKey="Giladi, Nir" sort="Giladi, Nir" uniqKey="Giladi N" first="Nir" last="Giladi">Nir Giladi</name></author><author><name sortKey="Hausdorff, Jeffrey M" sort="Hausdorff, Jeffrey M" uniqKey="Hausdorff J" first="Jeffrey M." last="Hausdorff">Jeffrey M. Hausdorff</name></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:AF3D10CAF6AA9E094C204DB3AB6F4D662B25DDB9</idno><date when="2008" year="2008">2008</date><idno type="doi">10.1111/j.1460-9568.2008.06167.x</idno><idno type="url">https://api.istex.fr/document/AF3D10CAF6AA9E094C204DB3AB6F4D662B25DDB9/fulltext/pdf</idno><idno type="wicri:Area/Main/Corpus">001868</idno><idno type="wicri:Area/Main/Curation">001621</idno><idno type="wicri:Area/Main/Exploration">000E58</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Bilateral coordination of walking and freezing of gait in Parkinson’s disease</title><author><name sortKey="Plotnik, Meir" sort="Plotnik, Meir" uniqKey="Plotnik M" first="Meir" last="Plotnik">Meir Plotnik</name><affiliation wicri:level="1"><country xml:lang="fr">Israël</country><wicri:regionArea>Movement Disorders Unit, Laboratory for Gait and Neurodynamics, Department of Neurology, Tel Aviv Sourasky Medical Center</wicri:regionArea><wicri:noRegion>Tel Aviv Sourasky Medical Center</wicri:noRegion></affiliation></author><author><name sortKey="Giladi, Nir" sort="Giladi, Nir" uniqKey="Giladi N" first="Nir" last="Giladi">Nir Giladi</name><affiliation wicri:level="1"><country xml:lang="fr">Israël</country><wicri:regionArea>Movement Disorders Unit, Laboratory for Gait and Neurodynamics, Department of Neurology, Tel Aviv Sourasky Medical Center</wicri:regionArea><wicri:noRegion>Tel Aviv Sourasky Medical Center</wicri:noRegion></affiliation><affiliation wicri:level="1"><country xml:lang="fr">Israël</country><wicri:regionArea>Department of Physical Therapy, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv</wicri:regionArea><wicri:noRegion>Tel Aviv</wicri:noRegion></affiliation><affiliation wicri:level="1"><country xml:lang="fr">Israël</country><wicri:regionArea>Department of Neurology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv</wicri:regionArea><wicri:noRegion>Tel Aviv</wicri:noRegion></affiliation></author><author><name sortKey="Hausdorff, Jeffrey M" sort="Hausdorff, Jeffrey M" uniqKey="Hausdorff J" first="Jeffrey M." last="Hausdorff">Jeffrey M. Hausdorff</name><affiliation wicri:level="1"><country xml:lang="fr">Israël</country><wicri:regionArea>Movement Disorders Unit, Laboratory for Gait and Neurodynamics, Department of Neurology, Tel Aviv Sourasky Medical Center</wicri:regionArea><wicri:noRegion>Tel Aviv Sourasky Medical Center</wicri:noRegion></affiliation><affiliation wicri:level="1"><country xml:lang="fr">Israël</country><wicri:regionArea>Department of Physical Therapy, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv</wicri:regionArea><wicri:noRegion>Tel Aviv</wicri:noRegion></affiliation><affiliation wicri:level="3"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division on Ageing, Harvard Medical School, Boston</wicri:regionArea><placeName><settlement type="city">Boston</settlement><region type="state">Massachusetts</region></placeName></affiliation></author></analytic><monogr></monogr><series><title level="j">European Journal of Neuroscience</title><idno type="ISSN">0953-816X</idno><idno type="eISSN">1460-9568</idno><imprint><publisher>Blackwell Publishing Ltd</publisher><pubPlace>Oxford, UK</pubPlace><date type="published" when="2008-04">2008-04</date><biblScope unit="volume">27</biblScope><biblScope unit="issue">8</biblScope><biblScope unit="page" from="1999">1999</biblScope><biblScope unit="page" to="2006">2006</biblScope></imprint><idno type="ISSN">0953-816X</idno></series><idno type="istex">AF3D10CAF6AA9E094C204DB3AB6F4D662B25DDB9</idno><idno type="DOI">10.1111/j.1460-9568.2008.06167.x</idno><idno type="ArticleID">EJN6167</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0953-816X</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>bilateral coordination</term><term>gait asymmetry</term><term>human locomotion</term><term>stepping phase</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Freezing of gait (FOG) in Parkinson's disease (PD) occurs most frequently during turns or step initiation, two tasks that likely demand a high degree of bilateral coordination between the legs. Our objective was to test the hypothesis that impairments in bilateral coordination of stepping are associated with FOG in PD. We compared locomotion features while walking on level ground between patients with PD that experience FOG (PD + FOG; n = 21) and patients with PD that do not (PD − FOG; n = 13). To study bilateral stepping coordination, we defined the stride duration of one foot as a gait cycle or 360°, determined the relative timing of contralateral heel‐strikes and defined this as the phase, ϕ (ideally, ϕ = 180°). The sum of the coefficient of variation of ϕ and the mean absolute difference between ϕ and 180° was defined as the phase coordination index (PCI), representing variability and inaccuracy, respectively, in phase generation. During the ‘Off’ state (= 12 h off anti‐parkinsonian medication), PCI values were higher (poorer coordination) in PD + FOG compared with PD − FOG (P < 0.024). Stride‐to‐stride phase adjustments, Δϕ, were also studied. Both groups scaled their ‘converging’ adjustments (towards 180°) to the same extent, but when generating diverging Δϕ (away from 180°), PD + FOG patients exhibited larger errors compared with PD − FOG patients (P < 0.006). This study demonstrates that patients with PD who experience FOG have distinctive impairments in the bilateral coordination of locomotion. Poor bilateral coordination of walking may predispose to FOG, especially during challenging tasks that demand a high degree of left–right coordination.</div></front></TEI><affiliations><list><country><li>Israël</li><li>États-Unis</li></country><region><li>Massachusetts</li></region><settlement><li>Boston</li></settlement></list><tree><country name="Israël"><noRegion><name sortKey="Plotnik, Meir" sort="Plotnik, Meir" uniqKey="Plotnik M" first="Meir" last="Plotnik">Meir Plotnik</name></noRegion><name sortKey="Giladi, Nir" sort="Giladi, Nir" uniqKey="Giladi N" first="Nir" last="Giladi">Nir Giladi</name><name sortKey="Giladi, Nir" sort="Giladi, Nir" uniqKey="Giladi N" first="Nir" last="Giladi">Nir Giladi</name><name sortKey="Giladi, Nir" sort="Giladi, Nir" uniqKey="Giladi N" first="Nir" last="Giladi">Nir Giladi</name><name sortKey="Hausdorff, Jeffrey M" sort="Hausdorff, Jeffrey M" uniqKey="Hausdorff J" first="Jeffrey M." last="Hausdorff">Jeffrey M. Hausdorff</name><name sortKey="Hausdorff, Jeffrey M" sort="Hausdorff, Jeffrey M" uniqKey="Hausdorff J" first="Jeffrey M." last="Hausdorff">Jeffrey M. Hausdorff</name></country><country name="États-Unis"><region name="Massachusetts"><name sortKey="Hausdorff, Jeffrey M" sort="Hausdorff, Jeffrey M" uniqKey="Hausdorff J" first="Jeffrey M." last="Hausdorff">Jeffrey M. Hausdorff</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/ParkinsonV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000E58 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000E58 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= ParkinsonV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= ISTEX:AF3D10CAF6AA9E094C204DB3AB6F4D662B25DDB9
|texte= Bilateral coordination of walking and freezing of gait in Parkinson’s disease
}}
| This area was generated with Dilib version V0.6.23. |  |